LDL Receptor Cycling to Lower LDL Cholesterol and Total Cholesterol

LDL receptors surface at one point in the plama membrane and then must migrate to anchoring proteins. Once anchored, LDL can interact with the LDL receptor and the LDL/LDL receptor complex enters our cell. The LDL receptor then dumps the LDL and resurfaces on the plasma membrane. Meanwhile the LDL is degraded so that the cholesterol can be used by that cell.