The old saying goes, too much of a good thing, can be a bad thing. This can apply to antioxidants as well. Like many other nutrients, getting the right amount of these nutrients is good to support a healthy body and help prevent disease, however too much can be problematic. There are a couple reasons why this is the case. First, these are active molecules that will take action even if free radical levels are in check. In fact, some research suggests that in excessive amounts in the body, antioxidants can actually begin to negatively interact with some of the same molecules that the free radicals go after. Also, too much of some antioxidants can hinder the potency of other antioxidants and essential nutrients. This is because that many of these nutrients have common mechanisms for absorption and circulation as well as destination tissues for activity and/or storage. Simply put, by loading up on a single or select few antioxidants you might be setting up an imbalance. Start with a balanced diet containing fresh or frozen fruits and vegetables as well as whole grains. Also, look for antioxidant supplement blends that provide efficacious levels without being excessive.